Operating positions for 2-port valves can be either shut (closed) so that no flow at all goes through, fully open for maximum flow, or sometimes partially open to any degree in between. Many valves are not designed to precisely control intermediate degree of flow; such valves are considered to be either open or shut. Some valves are specially designed to regulate varying amounts of flow. Such valves have been called by various names such as regulating, throttling, metering, or needle valves. For example, needle valves have elongated conically-tapered discs and matching seats for fine flow control. For some valves, there may be a mechanism to indicate by how much the valve is open, but in many cases other indications of flow rate are used, such as separate flow meters.
In plants with remote-controlled process operation, such as oil refineries and petrochemical plants, some 2-way valves can be designated as normally closed (NC) or normally open (NO) during regular operation. Examples of normally closed valves are sampling valves, which are only opened while a sample is taken. Examples of normally open valves are isolation valves, which are usually only shut when there is a problem with a unit or a section of a fluid system such as a leak in order to isolate the problem from the rest of the system.
Although many 2-way valves are made in which the flow can go in either direction between the two ports, when a valve is placed into a certain application, flow is often expected to go from one certain port on the upstream side of the valve, to the other port on the downstream side. Pressure regulators are variations of valves in which flow is controlled to produce a certain downstream pressure, if possible. They are often used to control flow of gas from a gas cylinder. A back-pressure regulator is a variation of a valve in which flow is controlled to maintain a certain upstream pressure, if possible.